Overview
Fluticasone is an inhaled corticosteroid used as a preventer medication for the long-term management of asthma and chronic obstructive pulmonary disease (COPD). It helps to reduce inflammation in the lungs.

Mechanism of Action
It works by mimicking natural corticosteroid hormones, binding to glucocorticoid receptors in the airways. This inhibits multiple inflammatory cells and mediators, effectively reducing airway swelling, mucus production, and hyperresponsiveness.

Dosage and Administration
It is typically inhaled once or twice daily, depending on the formulation and severity of the condition. Patients must rinse their mouths with water and spit it out after each use to prevent oral thrush.

Side Effects
Common side effects include oral candidiasis (thrush), hoarseness, and a sore throat. Systemic effects are rare but can occur at very high doses, including bone density loss and suppressed adrenal function.

Contraindications
Contraindicated in patients with a known hypersensitivity to fluticasone. It is not a rescue inhaler and should not be used for the primary treatment of status asthmaticus or acute asthma attacks.