培哚普利（Perindopril）
Overview
Perindopril is a long-acting ACE inhibitor effective in managing hypertension, symptomatic heart failure, and reducing the risk of cardiac events in patients with a history of myocardial infarction or revascularization.
Mechanism of Action
By inhibiting the ACE enzyme, it reduces the production of angiotensin II, leading to vasodilation, reduced blood pressure, and beneficial effects on the heart’s structure and function.
Dosage and Administration
The usual starting dose for hypertension is 4 mg once daily in the morning, which may be increased to 8 mg once daily.
Side Effects
Similar to other ACE inhibitors, a dry cough is common. Other potential side effects include headache, dizziness, and gastrointestinal disturbances.
Contraindications
Contraindicated in pregnancy, patients with a history of angioedema, and those with severe renal impairment.
Pregnancy and Lactation
Contraindicated during pregnancy. Use during breastfeeding is not recommended.
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