阿替洛爾（Atenolol）
Overview
Atenolol is a beta-1 selective adrenergic receptor blocker utilized primarily for the management of hypertension, angina pectoris, and acute myocardial infarction.
Mechanism of Action
It selectively blocks beta-1 receptors in the heart, reducing heart rate and the force of heart muscle contraction, which effectively lowers blood pressure.
Dosage and Administration
The typical starting dose for hypertension is 50 mg once daily, which may be increased to 100 mg daily if needed.
Side Effects
Side effects may include tiredness, cold extremities, slow heart rate, and gastrointestinal issues like nausea.
Contraindications
Contraindicated in patients with sinus bradycardia, heart block greater than first degree, cardiogenic shock, and overt cardiac failure.
Pregnancy and Lactation
Can cause fetal harm when administered to a pregnant woman. It is excreted in human milk; caution should be exercised.
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