替格瑞洛（Ticagrelor）
Overview
Ticagrelor is a potent antiplatelet medication used to prevent blood clots in patients with acute coronary syndrome or a history of myocardial infarction. It reduces the risk of cardiovascular death and stroke.
Mechanism of Action
It is a reversible antagonist of the P2Y12 ADP receptor on platelets, preventing platelet activation and aggregation, which are key steps in blood clot formation.
Dosage and Administration
Typically initiated with a 180 mg loading dose, followed by 90 mg twice daily for a year. It should be taken with low-dose aspirin (75-100 mg daily).
Side Effects
Bleeding is the most significant risk. Other common side effects include dyspnea (shortness of breath) and increased uric acid levels.
Contraindications
Contraindicated in patients with active pathological bleeding, a history of intracranial hemorrhage, or severe hepatic impairment.
Pregnancy and Lactation
Not recommended during pregnancy unless the potential benefit outweighs the risk. Discontinue nursing or the drug, considering the importance to the mother.
The medication usage, medical information, and related content provided on this website are for general informational purposes only. Under no circumstances should they be considered a substitute for professional medical advice, diagnosis, or treatment plans. Users must consult a registered doctor, pharmacist, or other qualified healthcare professional before making any medical decisions. Never disregard professional medical advice or delay in seeking it because of something you have read on this website. Do not use the information provided here to self-diagnose or treat any health issues or diseases.
Statement on Information Sources and Objectivity
The medical information and content presented on this website are based on widely recognised medical knowledge and public literature, and have been retrieved, translated, and compiled with the assistance of artificial intelligence (AI) tools. Details regarding disease symptoms, drug indications, mechanisms of action, and side effects are objective medical facts intended purely for general public education and reference.
Limitation of Liability
This website, and those who operate it, accept no legal liability for any of the following:
- Any direct or indirect consequences arising from a user's use of, or reliance on, the information provided on this website.
- Any adverse reactions, side effects, or other impacts resulting from the use of medications or treatments mentioned on this website.
- The accuracy, completeness, or timeliness of the information provided on this website (including content retrieved and compiled via AI).
If you are experiencing a medical emergency, please seek immediate professional medical assistance or call emergency services.
